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Updated: Jul 10, 2026

Monitoring Changes in Membrane Polarity, Membrane Integrity, and Intracellular Ion Concentrations in Streptococcus pneumoniae Using Fluorescent Dyes
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Monitoring Changes in Membrane Polarity, Membrane Integrity, and Intracellular Ion Concentrations in Streptococcus pneumoniae Using Fluorescent Dyes

Published on: February 17, 2014

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在Streptococcus pneumoniae能量合因子传送器ECF-PanTT上通过动态组合化学进行击中优化

Ioulia Antonia Exapicheidou1,2, Atanaz Shams1,2, Hamza Ibrahim3

  • 1Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) - Helmholtz Centre for Infection Research (HZI), 66123, Saarbrücken, Germany. anna.hirsch@helmholtz-hips.de.

Chemical communications (Cambridge, England)
|January 2, 2024
PubMed
概括

我们使用定向动态组合化学 (tdDCC) 发现了Streptococcus pneumoniae中ECF-PanT转运器的新抑制剂. 这种方法确定了具有改善活性的优化化合物,并揭示了它们的结合相互作用.

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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

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Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP009208:53

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