在丹麦使用艾滋病毒暴露前预防的使用者中,对子水感染的潜在查
Sofie Ellen Thomassen1, Sebastian von Schreeb1,2, Nikolai Søren Kirkby3
1Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen Denmark.
International journal of STD & AIDS
|January 2, 2024
概括
在丹麦,对使用HIV暴露前预防 (PrEP) 查无症状个体进行mpox (麻疹) 查是可行的. 这项研究发现,高风险人群中mopox的患病率很低,这表明例行查是可行的.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 2022年mopox (麻疹) 疫情主要影响同性恋,双性恋和其他与男性发生性关系的男性 (GBMSM).
- 在疫情爆发期间,Mopox测试在很大程度上仅限于有症状的个体.
- 在丹麦的艾滋病毒暴露前预防药物 (PrEP) 用户等无症状,高风险人群中使用mopox查的可行性尚未评估.
研究的目的:
- 评估在丹麦使用HIV PrEP的无症状个体中mopox查的可行性.
- 在这个高风险人群中评估mopox和其他性传播感染 (STIs) 的流行率.
主要方法:
- 在2022年秋季,丹麦两家PrEP诊所进行了一项前性查研究.
- 用于mopox PCR测试的直肠拭子被整合到PrEP用户的常规性感染性疾病查中.
- 收集了mopox,克拉米迪亚和淋病发病率的数据.
主要成果:
- 这项研究包括224名无症状男性 (平均年龄为36.5岁).
- 一名参与者 (0.4%) 的测试结果为mopox.positive.
- 克拉米迪亚的患病率为4.5%,淋病的患病率为4.0%.
结论:
- 在丹麦诊所中,Mpox查可用于 PrEP 用户的常规性传播感染查计划中.
- 低患病率表明,在高风险人群中可以有效实施有针对性的查.
相关概念视频
Infection
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Reservoir of Infection
Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Genital Herpes
Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Trichomoniasis
Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.


