骨矿物质密度与冠状动脉疾病患者冠状动脉斑负担之间的关联:使用定量计算断层扫描的横截面研究
Guang Geng1, Zhen Li2, Shuai Wang3
1Department of Medical Imaging, the Second Hospital of Hebei Medical University.
Coronary artery disease
|January 2, 2024
概括
在患有冠状动脉疾病 (CAD) 的男性中,骨矿物质密度 (BMD) 与冠状动脉化 (CAC) 相反相关,但与斑块负担无关. 在绝经后的女性中,BMD与CAC呈反向关联,但斑块负担并非如此.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 骨质疏松症研究研究
背景情况:
- 冠状动脉疾病 (CAD) 和骨质疏松症是普遍存在的慢性疾病.
- 了解骨矿物质密度 (BMD) 和冠状动脉化之间的关系对于全面的患者风险评估至关重要.
研究的目的:
- 调查腰椎骨矿物质密度 (BMD) 与冠状动脉化 (CAC) 和冠状动脉斑块负担之间的关联.
- 评估这些协会在已确诊动脉样硬化或CAD的患者.
主要方法:
- 一组290名男性和177名绝经后妇女确诊患有CAD,接受了计算机断层扫描 (CT) 来测量BMD (L1-L2).
- 冠状动脉分数 (CACS) 和修改的根西尼分数 (斑块负担) 被量化.
- 采用多变量回归和拉索回归分析来评估BMD,CACS和斑块负担之间的关联.
主要成果:
- 在男性中,BMD与CACS和CAC的存在相反相关,即使经过对混因子进行调整.
- 在绝经后的女性中, BMD 与未调整模型中的 CACS 和 CAC 存在相反相关,但这些关联在调整模型中没有持续存在.
- BMD与修改后的根西尼分数 (斑块负担) 或两性中CAD总体患病率没有相关性.
结论:
- 腰椎骨髓骨质损伤与CAD男性的冠状动脉化 (CAC) 相反相关.
- 经过对共变量进行调整后,在绝经后的妇女中没有一致观察到BMD和CAC之间的这种反向关联.
- 在患有CAD的男性或绝经后妇女中,没有发现BMD和冠状动脉斑块负担 (修改的根西尼得分) 之间的显著相关性.
更多相关视频
06:57Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection
Published on: September 22, 2023
1.0K
08:02Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
Published on: November 15, 2024
625
相关概念视频
01:10Computed Tomography
4.5K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.5K
01:20Imaging Studies for Cardiovascular System III: X-Ray
188
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
188