在恶性胆道收缩中胆道支架的性能
Bartosz Ostrowski1, Tomasz Marek2, Aleksandra Janczewska3
1Department of Gastroenterology and Hepatology, K. Gibiński University Clinical Center, Medical University of Silesia, Katowice, Poland. bartoszostrowski8@gmail.com
Polish archives of internal medicine
|January 2, 2024
概括
自扩展金属支架 (SEMS) 在恶性胆道狭窄症中比塑料支架 (PS) 更有效,提供更好的 bilirubin 减少,更短的住院时间和更长的通透性. 在这些患者中,SEMS是胆管排水的首选选择.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 医疗器械 医疗器械
背景情况:
- 内镜支架是恶性胆道狭窄的标准治疗方法.
- 使用的是自扩展金属支架 (SEMS) 和塑料支架 (PS).
研究的目的:
- 为了比较SEMSs与PSs在恶性狭窄的内镜胆道排水中的有效性.
- 为了优化恶性胆道狭窄的治疗策略.
主要方法:
- 对618名患有恶性胆道狭窄症的患者进行了回顾性分析,这些患者接受了1271次内镜逆行胆管瘤学术手术,并进行了支架 (2012-2017年).
- 从医院数据库中获得的至少3年的随访数据.
主要成果:
- 与PS相比,SEMS显示血清胆红素的降低幅度更大 (37%对32%,P=0.01).
- 使用SEMS的住院时间显著缩短 (9.5天 vs 11.8天,P<0.001).
- SEMS的穿透时间较长 (中位数为118天与46天,P<0.001),并发症较少 (12.9%与19.3%,P=0.001),并且成本效益更高.
结论:
- 自扩展金属支架 (SEMS) 在治疗恶性胆道狭窄方面显著优于塑料支架 (PS).
- 在患有恶性胆道狭窄的患者中,SEMS被推作为胆道排水的选择治疗.
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