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相关概念视频

Teratogenicity01:07

Teratogenicity

2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Birth Control Methods01:22

Birth Control Methods

265
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
265
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

456
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
456
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

172
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
172
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

736
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
736

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相关实验视频

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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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药物 堕胎和早产 药物 堕胎和早产

Byron Calhoun1

  • 1Professor and Vice-Chair of Obstetrics and Gynecology in the College of Medicine at the West Virginia University, Charleston, West Virginia. He is a diplomate of the American Board of Obstetrics and Gynecology with board certification in general Obstetrics and Gynecology and in the sub-specialty of Maternal-Fetal Medicine. He also is also board certified in Addictions Medicine.

Issues in law & medicine
|January 2, 2024
PubMed
概括

药物流产通常被认为是安全的,但关于早产风险的证据有限. 一些研究表明,需要手术完成的药物流产可能会增加PTB率,而仅仅是手术流产.

科学领域:

  • 生殖健康 生殖健康
  • 产科 产科 产科 产科 产科
  • 医疗干预 医疗干预

背景情况:

  • 药物堕胎被推广为手术堕胎的安全替代方案.
  • 关于药物堕胎和早产 (PTB) 之间的关联,目前仍在进行辩论.
  • 关于药物堕胎和PTB的现有证据有限.

研究的目的:

  • 审查有关药物堕胎和早产之间关系的现有证据.
  • 为了解决有关PTB的药物堕胎安全性的争议.

主要方法:

  • 关于药物堕胎和早产的现有文献的审查.
  • 分析了比较不同堕胎方法之间的PTB比率的研究.

主要成果:

  • 缺乏高质量的证据直接将药物流产与PTB联系起来.
  • 中等质量的证据表明,需要手术完成的药物流产与单独手术流产相比,增加了PTB率.

结论:

  • 关于PTB的药物流产的安全性需要进一步调查.
  • 特定类型的药物流产,特别是需要手术干预的药物流产,可能会增加早产的风险.

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