在恶性瘤的肺部手术中,术前营养干预的短期影响:单中心前性研究
Mamoru Takahashi1, Harutaro Okada2, Mako Kogaki3
1Department of Thoracic Surgery, Kyoto Katsura Hospital, 17 Yamada Hirao, Nishikyo, Kyoto, 615-8256, Japan. mt10947@kuhp.kyoto-u.ac.jp.
General thoracic and cardiovascular surgery
|January 2, 2024
概括
在肺癌患者手术前的营养干预是安全和可行的,显示了在手术前改善营养状况的潜力. 需要进一步的研究来证实肺癌患者接受手术的临床益处.
科学领域:
- 在瘤学瘤学.
- 手术营养是指手术营养.
- 临床研究 临床研究
背景情况:
- 手术前营养不良是肺癌手术不良结果的重要危险因素.
- 在手术前评估和解决营养状况对于手术候选人至关重要.
- 目前关于手术前营养干预在这个人群中的有效性的证据有限.
研究的目的:
- 评估手术前营养干预的安全性,可行性和短期治疗疗效.
- 研究营养干预对预后营养指数 (PNI) 的影响.
- 评估肺癌患者营养干预后的术后并发症率.
主要方法:
- 一项前性研究,包括15名患有临床I-III期非小细胞肺癌的患者.
- 资格标准包括术前预后营养指数 (PNI) < 45.
- 患者接受了手术前的营养干预,并对PNI和并发症率进行监测.
主要成果:
- 营养干预是安全和可行的,没有报道任何不良事件.
- 预后营养指数 (PNI) 在干预后显示出统计学上显著的改善 (p=0.04).
- 在15名研究患者中,术后并发症率为26.7%.
结论:
- 这是第一个详细介绍肺癌手术患者进行营养干预的PNI轨迹的前性研究.
- 术前营养干预证明了在这个患者群体中的安全性和可行性.
- 需要进行进一步的随机临床试验,以确定确定的临床疗效,并优化肺癌手术的干预措施.
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