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低氧诱导因子激活剂,roxadustat,增加了小鼠的肺血管抵抗

T Novák1, M Žaloudíková, P Smolková

  • 1Department of Physiology, Second Faculty of Medicine, Charles University, Prague 5, Czech Republic. vaclav.hampl@lfmotol.cuni.cz.

Physiological research
|January 2, 2024
PubMed
概括

作为低氧诱导因子 (HIF) 激活剂的罗克萨斯达特可能会增加肺血管抵抗力. 关于大鼠肺部的研究表明,在短期使用roxadustat时,肺高血压的风险较低,但建议对其进行监测.

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