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Updated: Jul 6, 2025

Assays for Validating Histone Acetyltransferase Inhibitors
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通过素脱乙酶抑制的代谢重编程优先针对NRF2-激活瘤

Dimitris Karagiannis1, Warren Wu2, Albert Li3

  • 1Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.

Cell reports
|January 2, 2024
PubMed
概括

肺腺癌与NRF2激活变得易受组织素脱乙酶 (HDAC) 抑制剂. 这是因为抑制HDAC会破坏NRF2-活性癌细胞存活所必需的代谢途径.

关键词:
CP: 癌症 癌症 癌症HDAC 抑制剂的使用通过NRF2路径.癌症表观遗传学 癌症表观遗传学癌症的代谢 癌症的代谢针对癌症的向治疗这是表观遗传重编程.肺癌是一种肺癌.

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