针治疗严重肌痛性肌痛症的影响:系统性审查和元分析
Hua Xue1, Li Zeng2, Hongxian He3
1Department of Neurology, Sichuan Taikang Hospital, Chengdu, Sichuan, China.
PloS one
|January 2, 2024
概括
针作为肌痛性肌痛症 (MG) 的辅助治疗方法具有前景,可以提高有效率并降低临床分数. 然而,需要更多高质量的研究来证实这些研究结果在MG中针疗效.
科学领域:
- 神经学 神经学
- 综合医学是一个整体医学.
- 临床研究 临床研究
背景情况:
- 骨髓灰质炎 (MG) 是一种慢性自身免疫神经肌肉疾病.
- 目前对MG的治疗有局限性.
- 针在治疗MG中的作用需要进一步研究.
研究的目的:
- 评估针作为肌痛性硬化症 (MG) 的辅助治疗方法的疗效.
- 综合了MG针随机对照试验 (RCT) 的证据.
主要方法:
- 对6个电子数据库进行了系统的搜索,搜索到2023年2月为止的MG针的RCT.
- 对包括的14个RCT进行了元分析.
- 结果包括有效率,传统中医 (TCM) 相对临床得分,绝对临床得分 (ACS),定量肌痛性骨髓灰质炎得分 (QMG),生活质量和不良事件.
主要成果:
- 与单独使用传统西方医学相比,针显著提高了有效治疗率 (OR = 4.28).
- 针降低了TCM相对临床评分 (WMD = -2.22),MG的ACS (WMD = -3.14),和QMG (WMD = -0.88) 的相对临床评分.
- 在包括的研究中,关于不良反应和生活质量的数据有限.
结论:
- 针可以作为一种有益的辅助疗法,用于肌痛性骨髓灰质炎.
- 它显示了提高治疗有效性和改善临床评分的潜力.
- 现有研究的整体低质量需要谨慎的解释,需要高质量的RCT来验证这些发现.
更多相关视频
07:29Author Spotlight: Development of a Standardized Acupuncture Tool Inspired by Advanced Techniques for Improved Safety and Precision
Published on: January 10, 2025
327
05:19Author Spotlight: An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension
Published on: September 1, 2023
1.5K
相关概念视频
01:20Myasthenia Gravis: Overview and Treatment
1.5K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.5K
01:15Myasthenia Gravis: Diagnostic Tests
861
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
861
01:26Chemical Synapses
8.8K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
8.8K
01:28Disorders of the Skeletal Muscle
955
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
955