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Updated: Jul 6, 2025

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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一个TLR4/TRAF6依赖的信号通路介导NCoR联合激活器复合体的形成,以激活炎症基因

Yohei Abe1, Eric R Kofman1,2,3, Zhengyu Ouyang1

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093.

Proceedings of the National Academy of Sciences of the United States of America
|January 2, 2024
PubMed
概括

收费类受体4 (TLR4) 信号将核受体核心压缩器 (NCoR) 转化为联合激活器. 这一途径涉及TRAF6,ERK1和TBK1,影响NFκB和AP-1基因激活.

关键词:
美国国家反腐败委员会 (NCoR)在PGC1β中.在TLR4中,在TRAF6中,巨细胞是一个巨细胞.

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