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Updated: Jul 6, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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小分子激动剂AdipoRon通过AdipoR1/AMPK/EGR4通路缓解糖尿病视网膜病变

Yihan Wang1,2,3,4,5,6, Yujuan Liu1,2,3,4,5, Junwei Fang1,2,3,4,5

  • 1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.

Journal of translational medicine
|January 3, 2024
PubMed
概括

阿迪波龙通过减少Müller细胞中的氧化应激和亡来保护糖尿病视网膜病变. 它激活AMPK通路并调节EGR4表达,为早期糖尿病视网膜病变治疗提供了一个新的治疗点.

关键词:
在 AdipoRon 中使用.糖尿病视网膜病变 - 糖尿病视网膜病变早期生长反应因子4氧化应激是一种氧化应激.

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