探索咖啡因摄入量和便秘之间的联系:一个使用国家健康和营养检查调查数据的横截面研究
1Department of Proctology, Northern Jiangsu People's Hospital, No.98 Nantong Western Road, Guangling District, Yangzhou, 225001, P.R. China.
高咖啡因摄入量与经历便秘的可能性较低有关. 养成饮用含咖啡因饮料的习惯可能有助于预防和缓解便秘症状.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 微生物组研究 微生物组研究
背景情况:
- 众所周知,咖啡因消费会影响胃肠道的运动性,并改变肠道微生物群.
- 便秘可能是由于结肠运动功能受损和结肠微生物群内的失生症引起的.
研究的目的:
- 调查咖啡因消费与便秘患病率之间的关系.
- 分析咖啡因摄入量如何影响经历便秘的几率.
主要方法:
- 一项采用国家健康和营养检查调查 (NHANES) 数据的横截面研究.
- 咖啡因摄入量通过24小时的饮食回忆量化.
- 便秘是根据自我报告的便一致性或频率来确定的.
- 使用后勤回归模型来确定关联,结果以几率比率 (OR) 和95%置信区间 (95%CI) 呈现.
- 根据年龄组进行了子组分析.
主要成果:
- 分析包括13,816名参与者,显示较高的咖啡因摄入量与便秘的几率降低有显著关联.
- 高咖啡因消费四分位数的调整后赔率比是:Q3:0.60 (95%CI:0.49-0.74),Q4:0.77 (95%CI:0.59-0.99),和Q5:0.72 (95%CI:0.56-0.92). 咖啡因消费四分位数的调整后赔率比是:Q3:0.60 (95%CI:0.49-0.74),Q4:0.77 (95%CI:0.59-0.99),和Q5:0.72 (95%CI:0.56-0.92). 咖啡因消费四分位数的调整后赔率比是:Q3:0.60 (95%CI:0.49-0.74),Q4:0.77 (95%CI:0.59-0.99),和Q5:0.72 (95%CI:0.56-0.92).
- 咖啡因摄入量和便秘之间的这种反向关联在年轻人和中年人群中是一致的.
结论:
- 较高的咖啡因消费量与较低的便秘几率有显著的关联.
- 研究结果表明,将含咖啡因的食物和饮料纳入饮食中可能是预防便秘和缓解便秘的策略.
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