Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

SNAREs and Membrane Fusion01:43

SNAREs and Membrane Fusion

10.9K
Once a transport vesicle has recognized its target organelle, the vesicular membrane needs to fuse with the target membrane to unload the cargo. Transmembrane proteins called SNAREs present on organelle membranes and their vesicles, mediate vesicle fusion.
SNAREs exist in pairs that symmetrically interact and catalyze the fusion of the lipid bilayers in vesicle and target organelle. v-SNARE in the vesicle membrane are single polypeptide chains that bind to a complementary t-SNARE, composed of 2...
10.9K
Fusion of Secretory Vesicles with the Plasma Membrane01:26

Fusion of Secretory Vesicles with the Plasma Membrane

11.1K
Proteins and neurotransmitters in secretory vesicles can be released from a cell upon vesicle docking, priming, and fusion with the plasma membrane. Vesicles are docked and primed in preparation for the quick exocytosis of their contents in response to a stimulus. The fusion process is mainly carried out by a SNAP Receptor or SNARE complex, consisting of synaptobrevin, syntaxin-1, and SNAP-25.
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
11.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Comparative effects of aerobic exercise intensity strategies on cardiorespiratory fitness and cardiometabolic risk factors in overweight and obese postmenopausal women.

Physical activity and nutrition·2026
Same author

Development of a recombinase polymerase amplification-lateral flow assay for rapid visual detection of Meloidogyne hapla.

Archives of microbiology·2026
Same author

Complete mitochondrial genome sequence of Koelreuteria paniculata (Sapindaceae) and comparative analysis within the family Sapindaceae.

Scientific reports·2026
Same author

Viral Capsid Protein Architecture Informed Selection of ssDNA Aptamers for Specific Detection of FMDV.

Analytical chemistry·2026
Same author

Storage conditions and antiviral efficacy of yeast-derived vacuoles on T4 virus.

Microbiology spectrum·2026
Same author

Fabrication of immune-enhancing vesicles from reassembled yeast vacuolar membranes.

Colloids and surfaces. B, Biointerfaces·2025

相关实验视频

Updated: Jul 6, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.4K

协同作用的囊泡载体系统用于有针对性的输送.

Christine Ardelle Marquez1, Cho-Im Oh1, Gna Ahn1,2

  • 1Department of Microbiology, Chungbuk National University, 1 Chungdae-Ro, Seowon-Gu, Cheongju, 28644, Republic of Korea.

Journal of nanobiotechnology
|January 3, 2024
PubMed
概括

膀载体系统 (VVS) 使用纳米技术提高药物输送的特异性. 本综述探讨了VVS类型,它们的合成,以及针对纳米尺度药物输送的未来潜力.

关键词:
药物输送系统 (DDS) 是一种药物输送系统.外基因组是外基因组中的一个.细胞外囊泡 (EV) 是一种细胞外囊泡.脂质细胞体中的脂肪体.有针对性的交付目标.气囊载体系统 (VVS) 是一种

更多相关视频

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

10.5K
Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

6.9K

相关实验视频

Last Updated: Jul 6, 2025

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
08:14

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting

Published on: October 26, 2018

8.4K
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
10:33

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Published on: July 23, 2016

10.5K
Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
09:12

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods

Published on: May 11, 2018

6.9K

科学领域:

  • 纳米技术纳米技术
  • 生物医学工程 生物医学工程
  • 药品制造 药品制造 药品制造

背景情况:

  • 药物输送系统 (DDS) 在实现目标特异性方面面临挑战.
  • 纳米技术的进步为精确的药物输送提供了新的解决方案.
  • 基于脂质的囊泡显示出作为向药物载体的前景.

研究的目的:

  • 审查囊泡载体系统 (VVS) 作为一种有针对性的药物输送方法.
  • 讨论不同的VVS修改策略及其属性.
  • 检查VVS的应用,挑战和未来.

主要方法:

  • 关于囊泡载体系统的文献综述.
  • 基于修改策略的VVS的分类:囊泡探针,囊泡囊泡和基因工程囊泡.
  • 分析每个VVS类型的合成,特性,应用和局限性.

主要成果:

  • 根据修改策略,确定了三种主要类型的VVS.
  • 突出合成方法和有利于有针对性的交付的优势性质.
  • 检查了 VVS 的当前应用,挑战和局限性.

结论:

  • 气囊载体系统为纳米尺度药物输送提供了高目标特异性.
  • 对VVS合成和工程的进一步研究可以克服目前的局限性.
  • VVS在先进的向治疗中具有显著的未来潜力.