由于体重增加而导致的COVID-19相关心血管疾病风险:全国范围的队列研究
Su Kyoung Lee1, Yohwan Lim2, Seogsong Jeong3
1Institute of Health and Environment, Seoul National University, Seoul, Korea.
在COVID-19大流行期间体重增加增加了所有人的心血管疾病 (CVD) 风险. 这包括那些感染了COVID-19的人和那些没有感染的人,强调了体重管理的重要性.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是全球发病率和死亡率的主要原因之一.
- 心血管疾病的发病率越来越高,特别是急性COVID-19后,需要进一步调查.
- COVID-19患者体重变化对心血管疾病风险的影响尚不清楚.
研究的目的:
- 研究COVID-19感染后体重变化与心血管疾病 (CVD) 风险之间的关联.
- 为了确定COVID-19患者体重增加是否有更高的心血管疾病事件风险.
- 在疫情背景下分析体重控制与心血管疾病风险之间的关系.
主要方法:
- 这是一项大型队列研究,涉及2017年至2020年期间选的2,024,728名成年人.
- 分析包括COVID-19组的70,996名参与者和对照组的212,869名参与者.
- 考克斯比例危险回归被用来计算身体质量指数 (BMI) 变化与心血管疾病风险的调整危险比率.
主要成果:
- 总共有2869个心血管疾病病例被确定.
- 稳定的BMI的COVID-19患者与稳定的BMI患者相比,心血管疾病的风险增加了2.28倍.
- 肥胖的非COVID-19患者也患有心血管疾病的风险高1.58倍.
结论:
- 疫情期间的体重增加,无论最初的体重类别如何,都会显著增加心血管疾病的风险.
- 流行病后体重增加的个人面临更高的心血管疾病风险,特别是那些患有COVID-19的人.
- 在大流行之前和期间保持稳定的体重对于减轻心血管疾病风险至关重要.
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