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Updated: Jul 6, 2025

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase G6PI-Induced RA Mice
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IKKε和TBK1可以预防RIPK1依赖和独立的炎症

Remzi Onur Eren1, Göksu Gökberk Kaya1, Robin Schwarzer1,2

  • 1Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.

Nature communications
|January 3, 2024
PubMed
概括

研究表明,IKKε补偿TBK1的损失,防止炎症. 这两种激酶的联合抑制会导致胚胎致死性和全身炎症,突出显示它们在组织稳态中的关键作用.

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