33个发展中国家的洪水暴露和怀孕流产
Cheng He1,2, Yixiang Zhu1, Lu Zhou1
1School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China.
Nature communications
|January 3, 2024
概括
洪水增加了发展中国家妇女的流产风险. 这种全球性健康问题不成比例地影响弱势群体,特别是在怀孕中后期.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 全球孕产妇健康问题
背景情况:
- 洪水影响全球数十亿人,而间接的健康后果往往被忽视.
- 发展中国家的弱势群体,特别是妇女,面临着环境灾害带来的未被充分研究的风险.
- 洪水对流产的具体影响仍然不太清楚.
研究的目的:
- 为了评估妊娠洪水暴露和怀孕流产之间的关联.
- 确定改变这种风险的人口和社会经济因素.
- 估计发展中国家与洪水相关的每年怀孕损失负担.
主要方法:
- 分析了来自33个发展中国家的90,465份妊娠流产记录.
- 与时空洪水数据库交叉引用怀孕损失数据.
- 统计建模以评估与洪水暴露相关的怀孕流产的几率比率.
主要成果:
- 孕期洪水暴露与1.08增加怀孕流产的几率有关 (95% CI:1.04-1.11).
- 在女性生殖年龄 (<21或>35) 之外的女性和怀孕中期到晚期期间观察到较高的风险.
- 对于依赖地表水的妇女,收入或教育水平较低的妇女,发现风险更高.
- 由于33个国家的洪水,每年估计有107,888例过度妊娠损失 (2010年).
- 在2010-2020年期间,过度妊娠损失的持续上升趋势,特别是在中美洲,加勒比海,南美洲和南亚.
结论:
- 暴露在洪水中显著增加了流产风险,突出了严重的环境健康威胁.
- 洪水加剧了孕产妇健康方面的差异,不成比例地影响了弱势妇女.
- 需要紧急干预,以减轻洪水对生殖健康的影响,在气候变化中.
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