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高左心室质量与发生糖尿病的风险增加有关
Shih-Ming Chuang1,2,3,4, Sung-Chen Liu1,2, Ching-Hsiang Leung2
1Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Scientific reports
|January 3, 2024
概括
通过心电图或心声图测量的左心室上层质量与糖尿病风险增加有关. 左心室缩可能是一个有用的标志物,用于识别患2型糖尿病的风险较高的人.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 左心室缩 (LVH) 与糖尿病风险之间的关联是有争议的.
- 电心电图 (ECG) 和回声心电图是评估LVH的常见方法.
研究的目的:
- 调查左心室质量指数 (LVMI) 与社区人口中发生糖尿病风险之间的关系.
- 为了确定通过心电图或心声学识别的LVH是否可以预测糖尿病的发展.
主要方法:
- 一组2696名参与者 (≥35岁,没有糖尿病) 接受了心电图和心声回声.
- 计算了左心室质量指数 (LVMI),并将参与者分为LVMI的第三类.
- 使用考克斯回归分析,在8.9年的中位随访期内追踪糖尿病发病率.
主要成果:
- 糖尿病的发病率和风险在较高的LVMI三位数中显著增加.
- 在同变量调整后,LVMI第三位最高的个体患糖尿病的风险增加了1.40倍 (HR 1.40,95% CI 1.06-1.91).
- 在患有高LVMI和ECG确定的LVH的参与者中,糖尿病风险最高,特别是在中国人群中.
结论:
- 通过心电图或心声学评估的左心室质量升高是发生糖尿病的独立预测因素.
- 通过这些成像方法识别的LVH可以在临床实践中作为糖尿病风险分层的有价值的替代标志物.
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