在歌鸟之间的迁徙分界中,基因调节和物种化
Matthew I M Louder1, Hannah Justen1, Abigail A Kimmitt1
1Biology Department, Texas A&M University, College Station, TX, USA.
Nature communications
|January 3, 2024
概括
鸟类迁徙行为的分子基础通过混合区的基因表达揭示出来. 昼夜基因和跨调节性变化是关键因素,有可能推动物种化.
科学领域:
- 进化生物学是进化的生物学.
- 行为遗传学行为遗传学
- 基因组学就是基因组学.
背景情况:
- 行为变异对于适应和物种化至关重要.
- 像迁移这样的复杂行为的分子基础并未得到充分理解.
- 混合区为研究行为差异的遗传基础提供了独特的机会.
研究的目的:
- 调查歌鸟亚种之间的迁徙行为差异的分子基础.
- 识别导致行为变异和生殖隔离的基因和调控机制.
主要方法:
- 分析了杂交歌鸟的五个大脑区域的基因表达.
- 在迁徙和非迁徙状态和亚种之间比较基因表达模式.
- 检查了杂交动物中cis-vs-trans-regulatory分歧和跨度表达的证据.
主要成果:
- 迁徙状态之间的基因表达差异主要是由所有大脑区域的昼夜基因驱动的.
- 与迁徙状态相互作用的亚种特定表达模式是特定于大脑区域的,可能保持生殖隔离.
- 证据表明,跨调节性变化,而不是 cis调节性变化,是观察到的表达差异的基础.
- 杂交表达水平往往与父母亚种相比是超越性的.
- 与核不相容性和应激反应相关的模式,有助于物种化.
结论:
- 昼夜基因在调节迁徙行为的过程中起着重要作用.
- 杂交物中的跨调节分歧和跨侵权表达是行为进化和物种化中的重要机制.
- 分子核不相容性可能会加剧杂交物种的选择,导致物种化过程.
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