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衰老的细胞类型特异性的分子特征在一个大脑范围的转录性细胞类型图书馆中揭示出来

Kelly Jin1, Zizhen Yao1, Cindy T J van Velthoven1

  • 1Allen Institute for Brain Science, Seattle, WA, USA.

bioRxiv : the preprint server for biology
|January 3, 2024
PubMed
概括

生物衰老会导致脑细胞平衡的逐渐丧失. 这项研究揭示了细胞类型特定的衰老变化,特别是在非神经细胞和下丘脑中,为大脑衰老机制提供了洞察力.

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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...