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相关概念视频

The Cochlea01:13

The Cochlea

45.0K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.0K
Hair Cells01:22

Hair Cells

40.5K
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
40.5K
Equilibrium and Balance01:15

Equilibrium and Balance

4.7K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.7K

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相关实验视频

Updated: Jul 6, 2025

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
09:35

Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis

Published on: July 18, 2011

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取决于速率的耳外毛细胞力量生成:模型和参数估计

Wen Cai, Karl Grosh

    bioRxiv : the preprint server for biology
    |January 3, 2024
    PubMed
    概括
    此摘要是机器生成的。

    外皮毛细胞 (OHCs) 使用普雷斯将电能转化为机械能,用于敏感听力. 我们的模型澄清了预先准备.

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    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
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    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

    Published on: May 24, 2018

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    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells
    05:55

    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells

    Published on: February 8, 2020

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    相关实验视频

    Last Updated: Jul 6, 2025

    Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis
    09:35

    Investigating Outer Hair Cell Motility with a Combination of External Alternating Electrical Field Stimulation and High-speed Image Analysis

    Published on: July 18, 2011

    13.5K
    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats
    09:23

    Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats

    Published on: May 24, 2018

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    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells
    05:55

    Dextran Labeling and Uptake in Live and Functional Murine Cochlear Hair Cells

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    科学领域:

    • 听觉神经科学 听觉神经科学
    • 生物物理学的生物物理.
    • 机械生物学 机械生物学

    背景情况:

    • 外皮毛细胞 (OHCs) 对于哺乳动物敏感的,频率特定的听力至关重要.
    • 膜蛋白质前被假设为OHCs提供了用于电机传导的压电性质.
    • 这种机制对于放大对低级声音的耳反应至关重要,但关键方面仍在争论中.

    研究的目的:

    • 调查速度依赖在OHC电机功能上的前列形状变化对OHC电机功能的影响.
    • 分析OHC跨膜阻抗在听觉转导中的作用.
    • 开发一个理论模型,结合速率依赖性,粘性弹性和压电性来理解OHC功能.

    主要方法:

    • 开发了OHC的理论电机模型.
    • 该模型明确包括构造过渡的速率依赖性,粘性弹性和压电性.
    • 拟议的实验以使用全细胞测量独特估计OHC构成性质.

    主要成果:

    • 证明了速率依赖性和粘性弹性的对OHCs电机力发电的影响.
    • 强调了适当的机械边界条件对于精确的跨膜电容估计的重要性.
    • 该模型为了解OHC功能背后的生物物理机制提供了一个框架.

    结论:

    • 速率依赖性和粘性弹性显著影响OHC电机力发电.
    • 准确估计OHC属性需要仔细考虑机械边界条件.
    • 这项研究为进一步研究听力机制提供了理论和实验基础.