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Updated: Jul 6, 2025

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
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Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

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酵母EndoG通过降解细胞质DNA来防止基因组不稳定

Yang Yu, Xin Wang, Jordan Fox

    bioRxiv : the preprint server for biology
    |January 3, 2024
    PubMed
    概括

    酵母Nuc1核酶通过降解细胞质DNA,如线粒体DNA (mtDNA) 和逆转移体cDNA,防止基因组的不稳定. 这种酶限制了核中有害的DNA插入,从而保持了基因组的完整性.

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    Combining Magnetic Sorting of Mother Cells and Fluctuation Tests to Analyze Genome Instability During Mitotic Cell Aging in Saccharomyces cerevisiae11:08

    Combining Magnetic Sorting of Mother Cells and Fluctuation Tests to Analyze Genome Instability During Mitotic Cell Aging in Saccharomyces cerevisiae

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