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Updated: Jul 6, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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局部化分子伴侣合成维持神经元树蛋白质稳定

Maria Vera Ugalde1, Célia Alecki1, Javeria Rizwan1

  • 1McGill University.

Research square
|January 3, 2024
PubMed
概括

神经元通过在蛋白质毒性压力期间将伴侣信使RNA (mRNA) 运送到树突上,从而增强蛋白质静止. 这涉及增加HSPA8mRNA翻译,对于预防神经退行至关重要.

关键词:
神经元神经元是一个神经元.骨髓缩侧面硬化症 (ALS) 是一种树状的树状物热冲击蛋白质是一种热冲击蛋白质.本地化翻译本地化翻译它们是mRNARNA.神经退行症的神经退行症蛋白质的平衡是蛋白质的平衡.单个分子光显微镜.

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