限时运动对活动节奏和心脏运动诱导的适应性的影响
Michael B Dial1, Elias M Malek1, Greco A Neblina1
1Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, 4505 S. Maryland Parkway, Bigelow Health Sciences (BHS) Building 323, Las Vegas, NV, 89154, USA.
在小鼠早期活跃阶段进行运动,与晚期活跃阶段相比,显著增强了心脏缩. 这种时间影响了运动适应和心血管健康.
科学领域:
- 时间生物学 时间生物学
- 运动生理学 运动生理学
- 心血管适应 适应心血管
背景情况:
- 循环节律对于心血管功能和新陈代谢至关重要.
- 运动诱导有益的心脏适应,包括缩,并影响昼夜节律.
研究的目的:
- 研究限时运动训练对运动诱导的心脏适应的影响.
- 检查运动时间对运动活动节律的影响.
主要方法:
- 雄性小鼠 (n=45) 在早期活跃期 (EAP),晚期活跃期 (LAP) 或保持久坐状态 (SED) 中进行了6周的自愿,时间限制的运动.
- 运动器官活动节奏在24小时内被评估.
- 分析了心脏重量,横截面积和基因/蛋白质表达 (线粒体和昼夜标志物).
主要成果:
- 与LAP小鼠相比,EAP小鼠的跑步距离明显大.
- 时间限制的运动改变了活动节奏,EAP小鼠表现出较早的缩期.
- 在LAP小鼠中,Per1基因表达率更高.
- 与LAP运动相比,EAP运动诱导了更大的心脏缩.
结论:
- 运动时间影响心肌适应.
- 早期活动期的运动促进心脏缩.
- 了解一天中的时间对运动反应的影响,可以优化心血管健康干预措施.
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