加纳私人保险高血压患者使用抗高血压药物的趋势
Afia Frimpomaa Asare Marfo1, John Serbe Marfo2, Jacob Plange-Rhule3
1Faculty of Pharmacy and Pharmaceutical sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. afamarfo.pharm@knust.edu.gh.
Journal of human hypertension
|January 3, 2024
概括
这项研究分析了加纳的抗高血压药物 (AHM) 模式,发现像CCB这样的常见药物类别经常被使用. 仿制药在单一产品处方中占主导地位,而品牌产品在固定组合中更为常见.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 高血压管理依赖于抗高血压药物 (AHM).
- 了解AHM的处方模式对于公共卫生倡议和治疗指南的遵守至关重要.
- 加纳特定的AHM利用数据提供了对国家处方趋势的洞察力.
研究的目的:
- 确定加纳国民人口中抗高血压药物 (AHM) 的处方模式.
- 分析AHM类,剂量,人口影响 (性别,年龄) 和通用状态.
- 为了估计药物使用量,按每天1000人群的确定每日剂量 (DDD) 计算.
主要方法:
- 对加纳2016年至2018年私人保险患者索赔数据的分析.
- 检查规定的AHM类,包括通道阻断剂 (CCB), ангиотензинII受体阻断剂 (ARB), ангиотензин转化酶抑制剂 (ACEI),利尿剂和β-阻断剂 (BB).
- 评估单一和固定组合AHM产品的通用和品牌地位.
主要成果:
- 通道阻断剂 (CCB) 是一个主要的类别,安洛迪平是最常用的单一药物.
- 阿姆洛迪平的使用量从2016-2017年的3.92 DDD/1000人/天增加到2018年的4.92.
- 在51-60岁的年龄组中,女性使用CCB几乎是男性使用的两倍 (74.0对38.3 DDD/1000人口/天).
- 在2018年,前十个AHM占所有单一药品的93%.
- 通用产品占单一AHM的大多数 (2018年为83.1%),而品牌产品占固定组合的主导地位 (2018年为91.3%).
结论:
- 在加纳观察到的AHM处方模式与临床预期一致.
- 虽然存在标准治疗指南,但它们对处方线的指导性影响需要进一步评估.
- 这些数据突出了特定的AHM类别的大量使用和CCB利用中的人口统计差异.
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