尾神经内分泌新生瘤:2023年的更新
Pernille Holmager1,2, Seppo W Langer3,4,5, Andreas Kjaer3,6
1ENETS Neuroendocrine Tumor Centre of Excellence, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. Holmager@dadlnet.dk.
Current oncology reports
|January 3, 2024
概括
对于1厘米以下或2厘米以上的尾神经内分泌瘤 (aNEN),建议分别进行简单或延伸尾切除术. 对1-2厘米的瘤进行扩展性手术是有疑问的,随访需要进一步研究.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内分泌学 在内分泌学.
背景情况:
- 尾神经内分泌瘤 (aNEN) 是一种罕见的瘤.
- 目前关于aNEN治疗的文献正在发展.
研究的目的:
- 审查最近关于aNEN治疗的文献.
- 评估aNEN的预后因素和后续策略.
主要方法:
- 关于过去5年发表的研究的文献综述.
- 对治疗指南和预后指标的分析.
主要成果:
- 对于小于1厘米的瘤,简单的尾切除术就足够了;对于大于2厘米的瘤,扩展的手术就足够了.
- 除了在特定情况下,对1-2厘米的aNEN进行扩展性手术没有显著的预后优势.
- 随访协议需要进一步验证,因为缺乏成像和生物标志物标准化.
结论:
- 小 (<1厘米) 和大 (>2厘米) aNENs 的手术管理是明确的.
- 对于中间 (1-2厘米) aNEN 进行扩展手术的必要性是有争议的.
- 未来的研究应该集中在淋巴结转移的影响和最佳的后续策略.
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