相关实验视频

Updated: Jul 6, 2025

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management

Published on: September 2, 2015

仿生人造皮肤具有完全可植入的无线触摸感官系统,用于伤口愈合和恢复皮肤触摸功能

Kyowon Kang¹, Seongryeol Ye^2,3, Chanho Jeong⁴

¹Department of Electrical and Electronic Engineering, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.

Nature communications

|January 3, 2024

概括

这项研究介绍了一种无线供电的人造皮肤系统,用于在严重皮肤损伤后恢复触觉. 该创新设备还有助于皮肤再生,并最大限度地减少不良反应,改善日常生活质量.

科学领域:

生物医学工程生物医学工程
再生医学是一种再生医学.
神经科学是一个神经科学.

背景情况:

触觉功能对于识别纹理和响应刺激至关重要.
由于烧伤,癌症或意外造成的严重皮肤损伤可能会导致永久的触觉感觉丧失.
这种功能障碍显著损害了个人的生活质量.

研究的目的:

引入一个完全可植入的无线驱动触觉感应系统嵌入人工皮肤 (WTSA).
恢复永久损坏的触觉功能,促进皮肤伤口的愈合和再生.
为了最大限度地减少与神经接口电极相关的异物反应.

主要方法:

制造具有广泛生物相容性的WTSA,用于触摸感官替代.
使用基于原蛋白和纤维素的人造皮肤 (CFAS) 来促进皮肤愈合.
在神经接口电极上涂上水凝涂层,以减少异物反应.
对腿部运动角度和电肌图 (EMG) 信号进行定量分析,以评估系统稳定性.

主要成果:

在WTSA成功地取代损坏的触觉感官结构.
该CFAS成分有效地促进皮肤伤口愈合和再生.
水凝涂层尽量减少了异物反应.
在不同压力强度下,WTSA显示传感系统运行稳定.

结论:

WTSA提供了一个有前途的解决方案,用于恢复永久性感官损失的个体的触觉功能.
该系统在感觉恢复和皮肤再生方面的双重能力解决了治疗严重皮肤损伤的关键需求.
生物相容的设计确保了稳定有效的长期性能.

更多相关视频

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Fabrication of the Composite Regenerative Peripheral Nerve Interface C-RPNI in the Adult Rat

Fabrication of the Composite Regenerative Peripheral Nerve Interface C-RPNI in the Adult Rat

Published on: February 25, 2020

相关概念视频

Sensory Functions of the Skin

Sensory Functions of the Skin

The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...