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Updated: Jul 6, 2025

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循环棕化调节TLR9信号传递和小鼠的系统性自身免疫

Hai Ni1,2, Yinuo Wang3,4, Kai Yao2

  • 1Department of Rheumatology and Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Nature communications
|January 3, 2024
PubMed
概括

棕基蛋白化酶1 (PPT1) 通过去除S-棕基酶离子S-palmitoylation从Toll-like受体9 (TLR9) 来调节系统性自身免疫. 抑制PPT1可以降低狼模型和患者的自身抗体和炎.

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