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Updated: Jul 6, 2025

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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Published on: December 14, 2017

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PPP2R2C的PAK6介导酸化调节了LRRK2-PP2A复合物的形成

Lucia Iannotta1,2, Marco Emanuele3, Giulia Favetta1

  • 1Department of Biology, University of Padova, Padua, Italy.

Frontiers in molecular neuroscience
|January 3, 2024
PubMed
概括

氨酸丰富的重复激酶2 (LRRK2) 酸化与帕金森病有关. PAK6激酶酸化PPP2R2C,影响其LRRK2结合和局部化,揭示了LRRK2活性的新调节机制.

关键词:
这是LRRK2在PP2A中,PP2A是PP2A.这就是PPP2R2C.在 Pak6 中使用.帕金森病是帕金森氏症的一种疾病.脱化脱化 脱化酸化的方法是:光化.

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