关于COVID-19和口腔粘膜病变的反思:系统性审查
Wai Ying Kot1, Jing Wen Li2, Alice Kit Ying Chan3
1Faculty of Dentistry, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Frontiers in oral health
|January 3, 2024
概括
本系统性审查检查了COVID-19患者的口腔粘膜病变. 是最常见的发现,但COVID-19和这些口腔病变之间的联系需要进一步调查.
科学领域:
- 口腔医学是指口腔医学.
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 与各种临床表现有关.
- 在COVID-19患者中报告了口腔粘膜病变,但其流行率和特征需要进一步澄清.
研究的目的:
- 提供有关COVID-19和口腔粘膜病变的临床更新.
- 分析COVID-19患者口腔粘膜病变的类型和患病率.
- 为了澄清COVID-19和口腔粘膜病变之间的潜在关联.
主要方法:
- 在主要数据库 (PubMed, Web of Science, Scopus, Cochrane Library) 和手动参考检查中进行了系统的文献搜索.
- 包括的研究以英语出版,重点关注COVID-19患者的口腔粘膜病变.
- 总共包括31项研究在审查中.
主要成果:
- 大多数研究都有中等到高的偏差风险.
- (未确定的诊断) 是最常见的口腔病变,其次是创伤性,角膜炎,,以及类似于口腔炎的病变.
- 统计分析显示了显著的异质性,表明结果的变化.
结论:
- 由于证据有限,COVID-19和口腔粘膜病变之间的关联仍然不清楚.
- 医疗保健专业人员应始终意识到COVID-19患者潜在的口腔表现.
- 需要进一步的研究来建立一个明确的联系,并了解潜在的机制.
相关概念视频
Assessment of the Mouth
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Herpes
Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Peptic Ulcer Disease III: Clinical Manifestations and Complications
Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant use.Gastric UlcersGastric ulcers share...


