复合的饮食抗氧化剂指数与延迟的生物衰老相关:一个基于人口的研究
Huiqin He1, Xin Chen1, Yiming Ding1
1Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University Medical School, Hangzhou 310016, China.
Aging
|January 3, 2024
概括
通过综合饮食抗氧化剂指数 (CDAI) 测量较高的饮食抗氧化剂摄入量与较慢的生物衰老有关. 这表明饮食在健康的衰老中起着关键作用.
科学领域:
- 营养科学 营养科学
- 老年学是一门学科.
- 流行病学 流行病学
背景情况:
- 关于饮食中抗氧化剂与生物衰老之间的联系的流行病学证据有限.
- 了解影响生物衰老的因素对于公共卫生至关重要.
- 综合饮食抗氧化剂指数 (CDAI) 量化了饮食中总体的抗氧化剂摄入量.
研究的目的:
- 调查CDAI与生物衰老之间的关联.
- 解决有关饮食和衰老的流行病学数据的差距.
- 探索饮食干预措施对健康衰老的潜力.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) (2001-2018) 的数据.
- 从24小时的饮食回忆中计算CDAI.
- 使用PhenoAge算法和加权多重回归模型确定生物年龄.
主要成果:
- 在CDAI和PhenoAge之间观察到一个显著的反向关系.
- 每个标准偏差增加的CDAI与生物年龄减少0.18年相关.
- 这种关联在各种人口统计和生活方式因素中保持一致.
结论:
- 较高的CDAI得分与延迟的生物衰老有关.
- 针对抗氧化剂摄入的饮食干预措施可能会促进健康的衰老.
- 这些发现支持饮食在调节衰老过程中的作用.
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