有机素石:设计,合成,ADMET预测,分子动力学研究和对乙胆酶和碳酸无水酶的抑制作用

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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Busra Ozturk Aydin1, Derya Aktas Anil2,3, Yeliz Demir4

  • 1Department of Chemistry, Faculty of Science, Ataturk University, 25240, Erzurum, Turkey.

Molecular diversity
|January 3, 2024
PubMed
概括

新型有机素石衍生物显示出对乙胆酶 (AChE) 和人类碳酸无水酶 (hCA) 的强烈抑制. 化合物16和19被确定为进一步药物开发的有希望的化合物.

关键词:
接收人 接收人乙烯基胆化酶是一种碳酸无水酶是一种碳酸无水酶.有机化合物石墨.

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