在非住院高风险成年人中存在SARS-CoV-2抗病毒处方缺口
Matthew E Levy1, Evanette Burrows1, Vanessa Chilunda1
1Helix, San Mateo, California, USA.
概括
很少有高风险患者接受了COVID-19抗病毒药物. 这项研究发现,只有31.9%的符合条件的非住院成年人接受了SARS-CoV-2的抗病毒治疗,这表明有很大的护理障碍.
科学领域:
- 传染性疾病 传染性疾病
- 临床药理学 临床药理学
- 公共卫生 公共卫生
背景情况:
- 由于COVID-19的流行,非住院患者需要有效的治疗,因为他们面临严重疾病的高风险.
- 抗病毒疗法对于减轻COVID-19的严重程度和减少医疗负担至关重要.
研究的目的:
- 在多州临床队列中评估SARS-CoV-2抗病毒处方模式.
- 确定非住院患者中服用抗病毒药物的情况,这些患者有严重COVID-19的危险因素.
主要方法:
- 一个多州临床队列的回顾性分析.
- 纳入标准:非住院成年人被诊断患有SARS-CoV-2和严重COVID-19的危险因素.
- 数据收集期:2022年4月至2023年6月.
主要成果:
- 总共有3247名成年人被纳入分析.
- 只有31.9%的符合条件的患者接受了抗病毒处方.
- 涅马特雷尔维尔/里托纳维尔是最常被处方的药物 (87.6%),其次是莫尔努皮拉维尔 (11.9%) 和雷梅西维尔 (0.5%).
结论:
- 高风险非住院COVID-19患者的抗病毒处方率仍然低于最佳水平.
- 在识别和治疗符合条件的患者方面可能存在重大障碍.
- 需要进一步的研究来了解和克服这些治疗障碍,以改善获得护理的机会.
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