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乌比基因酶Cbl和Cbl-b通过控制CSF-1R进口到巨体中来调节巨体的生长

Lu Huang1,2, Natalie W Thiex3,2, Jieqiong Lou1

  • 1Department of Chemistry and Biochemistry, South Dakota State University, Brookings, SD 57007.

Molecular biology of the cell
|January 3, 2024
PubMed
概括

乌比基连酶Cbl和Cbl-b通过调节CSF-1受体的内细胞分裂和信号传递来控制巨细胞的生长. 两种酶的丧失导致持续的增殖和巨细胞中基因表达的改变.

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