在危急疾病期间使用triiodothyronine
Matthew J Maiden1,2, Simon Forehan3
1Intensive Care Unit, The Royal Melbourne Hospital.
Current opinion in clinical nutrition and metabolic care
|January 3, 2024
概括
甲状腺激素 (T3) 水平在严重疾病下降,但试验表明恢复它们没有临床益处. 需要进一步的研究来确定T3.
科学领域:
- 内分泌学 在内分泌学.
- 关键护理医学 关键护理医学
- 代谢生理学 代谢生理学
背景情况:
- 在危急疾病期间,甲状腺激素生理学发生变化,循环三甲状腺素 (T3) 减少.
- 临床意义的降低T3在危急疾病仍有争议,不确定是否是病理或适应性.
- 有控制的临床试验对于评估恢复血清T3水平的治疗潜力至关重要.
结论:
- 虽然T3的管理使严重疾病的血清水平正常化,但目前的证据不支持其治疗疗效.
- 未来的研究应该调查潜在的T3治疗的最佳时间和疾病阶段.
- 探索超出血清T3度的替代标志物是必要的,以充分评估激素替代治疗的充分性.
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