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在细菌转录中 σ54 位移和促进物逃逸的结构基础

Forson Gao1, Fuzhou Ye1, Bowen Zhang1

  • 1Section of Structural and Synthetic Biology, Department of Infectious Disease, Imperial College London, London SW7 2AZ, United Kingdom.

Proceedings of the National Academy of Sciences of the United States of America
|January 3, 2024
PubMed
概括

通过sigma 54 (σ54) 启动细菌转录,涉及RNA聚合酶 (RNAP) 和DNA缩. 结构研究揭示了 σ54 和 DNA 相互作用的变化,使 RNAP 能够逃脱促进体并开始延长.

关键词:
的RNA聚合酶.冷电子显微镜的使用方法转录启动转录启动的 σ 因子.σ54 54 的时间.

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