相关实验视频

Updated: Jul 6, 2025

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
09:39

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Published on: February 13, 2018

9.6K

具有特征的急性发作小纤维神经病变

Thierry Gendre1, Jean-Pascal Lefaucheur1, Tarik Nordine1

  • 1From the Service de Neurologie (T.G., A.C.), CHU Henri Mondor APHP; Centre de Référence des Maladies Neuromusculaires Nord/Est/Ile-de-France (T.G., J.-P.L., T.N., F.-J.A., A.C.); Unité de Neurophysiologie Clinique (J.-P.L., T.N.), CHU Henri Mondor APHP; Unité de Recherche EA 4391 (J.-P.L., T.N., A.C.), Faculté de Santé, UniversitéParis Est Créteil; IMRB INSERM U955-Equipe 10 (Y.B.-A., F.-J.A.), UniversitéParis Est Créteil; Service d'Anatomo-Pathologie (F.-J.A.), CHU Henri Mondor APHP, Créteil; and Institut de Génomique Fonctionnelle (J.D.), Universitéde Montpellier, CNRS, INSERM, France.

Neurology(R) neuroimmunology & neuroinflammation
|January 3, 2024
PubMed
概括

急性小纤维神经病变 (AOSFN) 通常呈现为痛苦的,不依赖长度的神经病变. 实验室研究表明免疫系统的参与,许多患者在接受皮质类固醇治疗后表现出改善.

更多相关视频

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay08:33

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay

Published on: June 25, 2019

8.3K
Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies11:22

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies

Published on: April 29, 2013

13.2K

相关概念视频

Chemical Synapses01:26

Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
8.8K
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
861
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.5K