早期儿童多重或持续的调节问题和年轻成年人的白天唾液皮质醇
Ayten Bilgin1, Kati Heinonen2, Polina Girchenko3
1Department of Psychology, University of Essex, Colchester, United Kingdom.
Psychoneuroendocrinology
|January 3, 2024
概括
持续的早期儿童调节问题 (RP) 与成年期的皮质醇水平较高有关,这表明生理途径以后的行为问题. 这项研究探讨了与早期RP相关的长期HPA轴活性.
科学领域:
- 发展心理学 发展心理学
- 神经内分泌学神经内分泌学
- 儿童健康 儿童健康
背景情况:
- 儿童早期的调节性问题 (RP),如哭泣,睡眠或食问题,与成人行为问题有关.
- 垂体-垂体-上腺 (HPA) 轴可能会调解这种联系,但其与成年期早期RPs相关的活动尚不清楚.
研究的目的:
- 调查幼儿时期多次或持续的RP与年轻成人时的白天唾液皮质醇水平之间的关联.
主要方法:
- 在308名5,20岁和56个月的儿童中使用家长采访和神经学评估评估RP.
- 定义了多个RP (两个或三个在5个月) 和持久的RP (至少一个在5,20和56个月).
- 使用混合模型和通用线性模型,在平均年龄为25.4岁的参与者中测量了白天唾液皮质醇.
主要成果:
- 持续的RP与在清醒期间显著更高的皮质醇峰值和输出有关.
- 持续的RP也与皮质醇唤醒反应的增加有关.
- 然而,多个RP显示,与唾液皮质醇水平没有显著的关联.
结论:
- 在童年早期患有持续性RP的儿童在20年后显示HPA轴活动增加.
- 这种增强的活动,特别是在应对唤醒的压力时,可能代表一个生理机制,将早期的RP与成人行为结果联系起来.
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