过高血糖症对肝细胞癌的跨动脉化学栓塞后并发症和死亡率的影响
Sun Joon Moon1,2, Chang Ho Ahn1,3, Yun Bin Lee1,4
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Diabetes & metabolism journal
|January 3, 2024
概括
通过动脉化学栓塞 (TACE) 期间高血糖会增加并发症的风险. 对于接受TACE的患者,特别是糖尿病患者,有效的周围手术血糖控制至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 内分泌学 在内分泌学.
- 干预性放射学 干预性放射学
背景情况:
- 缺乏在非手术性侵入性手术中进行血糖控制的指导方针,例如肝细胞癌的跨动脉化学血栓化 (TACE).
- 糖尿病和高血糖是TACE后并发症的潜在危险因素.
研究的目的:
- 调查糖尿病和不同水平的高血糖与TACE后并发症之间的关联.
- 为了评估周围手术血糖控制对TACE后患者结果的影响.
主要方法:
- 从2005年至2018年间,对22,159个TACE程序进行了回顾性分析.
- 评估DM,HbA1c和周围过程葡萄糖之间的关联,其结果包括细菌病,AKI,延迟出院和14天死亡率.
- 倾向性得分匹配用于比较患有和没有DM的患者.
主要成果:
- 术周平均葡萄糖与细菌病,AKI,延迟出院和14天死亡率有显著联系.
- 糖尿病与细菌病和AKI有关.
- 与≤126 mg/dL水平相比,平均葡萄糖水平升高 (202 mg/dL以上的细菌病,181 mg/dL以上的AKI) 会增加并发症风险.
结论:
- 周围的平均葡萄糖水平,而不是HbA1c,与TACE后的不良结果相关.
- 强调了在周围手术期间控制血糖的关键作用,以减轻TACE后的并发症.
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