昼间温度范围与精子质量之间的关联:来自中国中部前性队列的证据
Yubo Ma1, Ye He2, Dongdong Tang2
1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, China; The Key Laboratory of Major Autoimmune Diseases, 81 Meishan Road, Anhui Medical University, Hefei, Anhui, China.
The Science of the total environment
|January 3, 2024
概括
每天的温度波动会影响男性的生育能力. 较低的日间温度范围 (DTR) 对精子质量产生了负面影响,而较高的DTR则显示出积极的影响,特别是在较冷的环境中.
科学领域:
- 环境健康 环境健康
- 生殖生物学 生殖生物学
- 精子质量评估 精子质量评估
背景情况:
- 以前的研究将日间温度变化与城市层面的精子质量联系起来.
- 对日内温度变化对个体精子质量影响的研究有限.
研究的目的:
- 调查日间温度范围 (DTR) 暴露与男性生殖参数之间的线性和非线性关联.
- 分析个人对DTR的暴露及其对精子质量的影响.
主要方法:
- 利用了来自安前性辅助生殖队伍的数据,包括15112名男性和28267名精液分析.
- 在精液分析前0-90天,评估对环境因素的个人暴露,包括DTR.
- 采用线性混合模型,自然立方线和子组分析来确定关联.
主要成果:
- 观察到DTR与总运动率,精子度,精子计数,总运动精子计数和渐进运动精子计数之间的显著"U"形非线性关联.
- 较低的DTR水平对精子参数产生了负面影响,而较高的DTR水平显示出了积极的影响.
- 这些效应在环境温度低于16.5°C时更加明显,这表明在较冷的条件下敏感性增加.
结论:
- 精子质量对日间温度范围 (DTR) 暴露敏感,特别是在较冷的环境中.
- 个人温度管理策略对于缓解精子质量下降至关重要.
- 促进碳中和性的政策可能会提高人口层面的精子质量.
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