相关实验视频
Updated: Jul 6, 2025
06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
23.5K
目前关于高级上下皮层癌的局部治疗方法的证据
Otilia Kimpel1, Ulrich Dischinger1, Barbara Altieri1
1Division of Endocrinology and Diabetes, Department of Medicine, University Hospital, University of Würzburg, Würzburg, Germany.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
|January 3, 2024
概括
局部疗法 (LT) 为晚期上腺皮癌 (ACC) 提供安全有效的治疗选择,特别是在有限的疾病中. 有证据表明,疾病控制和部分反应是可以实现的,指导临床实践.
科学领域:
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 国际指导方针建议针对晚期上腺皮层癌 (ACC) 进行局部治疗 (LT).
- 评估LT对ACC的大规模研究是有限的,需要综合证据.
研究的目的:
- 审查和综合当前关于高级ACC局部疗法的证据.
- 根据现有的文献,制定临床指导.
主要方法:
- 在PubMed数据库的系统文献搜索.
- 包括21项回顾性研究,分析了374名接受各种LT (放射治疗,化学栓塞,放射栓塞,热性切除) 的患者.
主要成果:
- 在大多数患者中,放射治疗显示出疾病控制和部分反应,通常具有息意图.
- 其他LT在显著的患者百分比中显示出局部疾病控制.
- 无病间隔>9个月和病变<5厘米的患者可能受益最多.
结论:
- 对于晚期ACC,对LT的现有证据有限,但表明对局部疾病的安全性和有效性.
- 应在多学科团队方法中考虑LT,利用当地专业知识.
相关概念视频
01:27Tumor Immunotherapy
529
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
529
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
02:57Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K