相关实验视频
Updated: Jul 6, 2025

06:25
A Method for Islet Transplantation to the Omentum in Mouse
Published on: January 7, 2019
11.1K
关于移植后糖尿病的国际共识
Adnan Sharif1,2, Harini Chakkera3, Aiko P J de Vries4,5
1Department of Nephrology and Transplantation, University Hospitals Birmingham, Birmingham, United Kingdom.
概括
这一共识更新解决了实体器官移植接受者的移植后糖尿病 (PTDM). 它提供有关PTDM诊断,预防和管理的专家意见,以减少临床实践的变化.
科学领域:
- 移植医学 移植医学
- 内分泌学 在内分泌学.
- 临床实践指南 临床实践指南
背景情况:
- 移植后糖尿病 (PTDM) 是固体器官移植后的一种严重并发症.
- 2003年和2013年之前的共识会议建立了PTDM诊断,风险分层和管理的框架.
- 最近PTDM知识和糖尿病治疗方面的进展需要对临床指南进行更新.
研究的目的:
- 更新关于移植后糖尿病 (PTDM) 的国际共识声明.
- 为最佳诊断工具,糖尿病前期识别和PTDM管理策略提供专家意见.
- 引导未来的研究方向,以改善PTDM护理和移植受体的长期结果.
主要方法:
- 在2022年5月6日至8日,在奥地利维也纳召开了第三届国际PTDM共识会议,与全球专家一起.
- 关于PTDM诊断,糖尿病前期,机制性见解,免疫抑制,预防和治疗的意见表达.
- 承认缺乏高质量的证据,排除了GRADE建议.
主要成果:
- 协商一致会议产生了关于PTDM各方面的最新意见.
- 涵盖的关键领域包括诊断标准,糖尿病前期,免疫抑制修饰和新型降糖剂.
- 报告强调了专家的共识,因为有限的强有力的证据,特别是对于脏移植接受者.
结论:
- 本报告反映了专家的共识意见,以解决更新PTDM指导的需要.
- 这些意见表旨在减少在实体器官移植队列中对PTDM诊断和管理的临床实践差异.
- 进一步的研究对于生成优化PTDM护理和改善长期结果的强有力的证据至关重要.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.4K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.4K
Diabetes: Symptoms, Diagnosis, and Complications
549
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
549
Diabetes Mellitus: Overview and Type I Subtype
2.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.7K
Pathophysiology of Diabetes
941
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
941
Diabetes: Management and Pharmacotherapy
285
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
285
Tissue Transplantation
372
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
372

