免疫功能低下患者中COVID-19 mRNA疫苗接种趋势
Bojan Lazarevic1, Allison R Casola1, Christopher V Chambers1
1From the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA (BL); Department of Family and Community Medicine, Thomas Jefferson University, Philadelphia, PA (ARC, CVC).
Journal of the American Board of Family Medicine : JABFM
|January 3, 2024
概括
免疫功能低下患者的COVID-19疫苗接种趋势表明,虽然大多数患者接受了3个以上的mRNA剂量,但存在差异,特别是在黑人和白人患者之间. 初级保健应专注于以患者为中心的疫苗教育,以提高疫苗接种率.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 免疫功能低下的人面临严重COVID-19的更高风险.
- 评估疫苗接种趋势对于公共卫生战略至关重要.
研究的目的:
- 评估城市初级保健机构中免疫力低下患者的COVID-19疫苗接种模式.
- 为了确定这个脆弱人群中mRNA疫苗接种的趋势.
主要方法:
- 从2021年1月到2022年5月,对887名免疫受损患者的回顾性图表审查.
- 收集的数据包括人口统计,诊断和COVID-19 mRNA疫苗接种状态 (剂量和类型).
- 用描述性统计和对对 t 测试进行分析.
主要成果:
- 62.7%的患者接受了3个或更多的mRNA疫苗剂量;37.3%接受了2个或更少.
- 固体瘤 (62.6%) 和艾滋病 (23.8%) 是常见的诊断.
- 报告指出,与白人患者相比,有42%的黑人患者接受了2剂或更少的剂量.
结论:
- 尽管总体接种率很高,但在免疫功能低下的患者中,在接种COVID-19疫苗方面存在显著的种族差异.
- 初级保健提供者必须加强以患者为中心的教育,以解决这些差异.
- 有针对性的宣传对改善弱势群体的疫苗接种覆盖率至关重要.
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