癌症疼痛患者的认知功能及其相关因素:在中国进行的一项多中心横截面研究
Hongyu Zhu1, Rongbo Lin1, Jianyi Wang2
1Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China.
BMJ open
|January 3, 2024
概括
认知障碍 (CI) 影响了中国超过三分之一的癌症疼痛患者. 老年,吸烟,睡眠不足和心理健康问题等因素增加了CI风险,需要个性化干预.
科学领域:
- 在瘤学瘤学.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 癌症疼痛 (CP) 显著影响患者的生活质量.
- 认知障碍 (CI) 是癌症患者的一种已知的并发症.
- 了解CI在CP中的贡献因素对于有效管理至关重要.
研究的目的:
- 评估中国大陆癌症疼痛患者的认知功能水平.
- 在这个人群中识别与认知障碍相关的因素.
主要方法:
- 在三个三级瘤医院进行了一项描述性的横截面研究.
- 220名患有癌症相关疼痛的住院患者填写了经过验证的问卷.
- 用FACT-Cog尺度评估认知障碍;逻辑回归确定了相关因素.
主要成果:
- 在癌症疼痛患者中,认知障碍的患病率为35.90%.
- 与CI几率增加相关的因素包括:癌症疼痛,抑郁症,焦虑,老年,睡眠质量差以及吸烟史.
- 45%的人表示睡眠质量差,28.2%的人表示中度至重度疼痛,64.6%的人表示抑郁,38.6%的人表示焦虑.
结论:
- 在中国的癌症疼痛患者中,认知障碍很普遍.
- 高龄,吸烟,睡眠不良,严重疼痛,抑郁和焦虑是CI的重要危险因素.
- 针对这些决定因素的个性化干预措施对于癌症患者的CI管理至关重要.
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