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通过 thiolated cyclodextrins 抑制 P-glycoprotein 介导的排泄物

Florina Veider1, Soheil Haddadzadegan1, Eva Sanchez Armengol1

  • 1Center for Chemistry and Biomedicine, Department of Pharmaceutical Technology, Institute of Pharmacy, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.

Carbohydrate polymers
|January 3, 2024
PubMed
概括

化β-环氧素 (β-CD-SHs) 有效抑制了Caco-2细胞中的P-glycoprotein (P-gp) 流量. 这项研究表明β-CD-SHs可以增强药物吸收并减少药物排放,从而提供潜在的制药应用.

关键词:
素-AMAM是一种素.细胞吸收的时间流动性 流动性 流动性抑制剂是一种抑制剂.罗达明 123 123 罗达明硫酸化循环德克斯特林.这种类型的基因组是 thiomers.

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