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[开发具有优异细胞内保留功能的光学探针]

Minoru Kawatani1,2, Mako Kamiya1, Yasuteru Urano2,3

  • 1Department of Life Science and Technology, Tokyo institution of Technology.

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
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PubMed
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新的可激活光探针可以防止水解产品的泄漏,从而能够长期跟踪和改善细胞中酶活性的成像. 这一突破增强了标记基因和癌症的可视化.

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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