不同类型的金属支架在恶性远端十二指肠狭窄症的临床结果:一项回顾性研究
Hau-Jyun Su1, Chieh-Chang Chen2, Yu-Ting Kuo3
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Journal of the Formosan Medical Association = Taiwan yi zhi
|January 3, 2024
概括
未覆盖和部分覆盖的金属支架对恶性远端十二指肠狭窄有效. 支架功能障碍是一个问题,特别是在老年患者中,需要进一步的研究以改善结果.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 在瘤学瘤学.
背景情况:
- 恶性远端十二指肠狭窄症 (MDDS) 由于十二指肠解剖学而带来独特的支架挑战.
- 关于远端十二指肠支架的临床结果的研究有限.
研究的目的:
- 为了比较未覆盖的自扩展金属支架 (UC-SEMS) 和部分覆盖的自扩展金属支架 (PC-SEMS) 在治疗MDDS的临床结果.
- 为了确定与MDDS患者的支架功能障碍相关的因素.
主要方法:
- 从2012年至2020年,对56名接受了十二指肠支架 (35名UC-SEMS,21名PC-SEMS) 的MDDS患者进行了回顾性分析.
- 在UC-SEMS和PC-SEMS组之间比较临床成功率,支架功能障碍和穿透率.
- 多变量分析以确定支架功能障碍的预测因素.
主要成果:
- 对于UC-SEMS和PC-SEMS,临床成功率相似 (85.7%).
- 两组之间在支架功能障碍率 (34.3%与38.1%) 或通透率 (117.2与100.0天) 上没有显著差异.
- 年龄≥65岁是支架功能障碍的重要危险因素 (OR:4.78,p=0.031).
结论:
- 无论UC-SEMS还是PC-SEMS都证明了MDDS治疗的安全性和有效性.
- 支架功能障碍是一个重大挑战,特别是在老年患者中.
- 需要进一步的研究来提高支架安置的有效性,并减少功能障碍的风险.
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