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Updated: Jul 6, 2025

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开发一种以人类遗传学为指导的优先评分,用于19,365个基因和399种药物适用性

Áine Duffy1,2, Ben Omega Petrazzini1,2,3, David Stein1,2,4

  • 1The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.

Nature genetics
|January 3, 2024
PubMed
概括

使用人类遗传证据优先考虑药物标,提高了药物发现的成功率. 一个新的遗传优先分数 (GPS) 和它的定向版本增强了临床试验的目标选择.

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