使用分子方法来界定诺罗病毒爆发:一个系统的审查
Luqiu Tao1,2, Xinyang Zhang1,2, Xuan Wang1
1Nanjing Municipal Center for Disease Control and Prevention affiliated to Nanjing Medical University, Zizhulin 2, 210003, Nanjing, Jiangsu, China.
Archives of virology
|January 3, 2024
概括
这项研究建议使用单核酸多态性 (SNP) 率来定义诺罗病毒爆发. 低于0.20%的SNP率表明严格的相似性,而低于0.50%的SNP率表明诺罗病毒菌株的相似性放松.
科学领域:
- 流行病学 流行病学
- 病毒学 病毒学
- 基因组学就是基因组学.
背景情况:
- 诺罗病毒是全球急性胃肠炎的主要原因.
- 评估诺罗病毒爆发关系依赖于单核酸多态化 (SNP) 分析.
- 目前还没有标准化值来对疫情菌株进行聚类.
结论:
- 低于0.20%和0.50%的SNP率可以作为分别在疫情中的诺罗病毒菌株相似性的严格和宽松的门.
- 需要进一步的研究来完善这些值,并了解疫情中的和疫情之间的变化.
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