针对轻度认知障碍或痴呆症患者的记忆功能的计算机认知训练:系统性审查和元分析
Aaron T C Chan1, Roy T F Ip1, Joshua Y S Tran1
1JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
NPJ digital medicine
|January 3, 2024
概括
计算机认知训练 (CCT) 在轻度认知障碍 (MCI) 患者中显著改善记忆功能. 监督的CCT显示了更广泛的益处,而无监督的CCT提供了一个方便的家庭选择来增强口头记忆.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 心理学 心理学 心理学
背景情况:
- 痴呆症影响着日益老龄化的人口,需要进行非药物干预.
- 认知干预旨在提高老年人的认知功能.
- 轻度认知障碍 (MCI) 和痴呆症是老年人群的重大问题.
研究的目的:
- 评估计算机化认知训练 (CCT) 对MCI或痴呆症患者记忆功能的有效性.
- 为了比较监督与无监督CCT在各种内存领域的影响.
- 综合来自CCT随机对照试验的证据,以提高记忆力.
主要方法:
- 35个随机对照试验的元分析.
- 在MEDLINE,Embase,PsycINFO和谷歌学者中进行的搜索.
- 提取神经心理评估得分来计算标准化平均差异 (SMD).
主要成果:
- 在MCI患者中,CCT改善了口头,视觉和工作记忆 (SMD分别为0.55,0.36,0.37).
- 与未经监督的CCT相比,监督的CCT在内存域中显示出更大的改善.
- 没有监督的CCT改善了口头记忆 (SMD 0.21),CCT改善了痴呆症的口头记忆 (SMD 0.64).
结论:
- 计算机化认知训练 (CCT) 有效改善MCI患者的各种记忆领域.
- 监督的CCT产生了更显著的认知益处,但无监督的CCT提供了一个可访问的,基于家庭的替代方案.
- 需要进一步的研究来解决异质性问题,并确认痴呆症患者群体的发现.
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