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Updated: Jul 6, 2025

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
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在韩国基因组和流行病学研究中,高灵敏度C反应蛋白与血清尿酸相关的纵向变化

Anthony Kityo1, Sang-Ah Lee2,3

  • 1Department of Preventive Medicine, School of Medicine, Kangwon National University, Gangwon, 24341, Republic of Korea.

Scientific reports
|January 3, 2024
PubMed
概括

在一项大型队列研究中,高血清尿酸 (SUA) 水平与炎症标志物高灵敏性C反应蛋白 (hs-CRP) 的增加有关. 这表明SUA可能在慢性炎症中起作用.

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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